- Aché
Paraguay (Canindeyú, Caaguazú, Alto Paraná, Caazapá)
- Achi
Guatemala (Baja Verapaz: Rabinal, Cubulco, San Miguel Chicaj, Salamá)
- Akateko
Guatemala (Huehuetenango: San Miguel Acatán, San Rafael La Independencia) · Mexico (Chiapas, Campeche, Quintana Roo)
- Ñomndaa
Mexico (Guerrero: Xochistlahuaca, Tlacoachistlahuaca, Ometepec; Oaxaca: San Pedro Amuzgos, Santa María Ipalapa)
- Angaité
Paraguay (Presidente Hayes, Boquerón, Alto Paraguay)
- Ava Guarani
Paraguay (Canindeyú, Alto Paraná, Amambay, San Pedro) · Brazil (Mato Grosso do Sul, Paraná, São Paulo) · Argentina (Misiones)
- Awakateko
Guatemala (Huehuetenango: Aguacatán)
- Ayoreo
Paraguay (Alto Paraguay, Boquerón) · Bolivia (Santa Cruz)
- Bileez Kriol
Belize
- Lakty'añ
Mexico (Chiapas: Tila, Tumbalá, Sabanilla, Salto de Agua, Palenque; Tabasco; Campeche)
- Ch'orti'
Guatemala (Chiquimula: Jocotán, Camotán, Olopa, San Juan Ermita) · Honduras (Copán)
- Chalchiteko
Guatemala (Huehuetenango: Aguacatán, Chalchitán area)
- Ishir
Paraguay (Alto Paraguay: Bahía Negra, Puerto Diana, Fuerte Olimpo and nearby communities)
- Cha'jna'a
Mexico (southern Oaxaca: Santos Reyes Nopala, Santa Catarina Juquila, San Juan Quiahije, Zenzontepec and nearby)
- Chichimeca Jonaz
Mexico (Guanajuato: Misión de Chichimecas, San Luis de la Paz)
- Chinantec
Mexico (northern Oaxaca: Chinantla region; Veracruz)
language family or group - Chontal
Mexico (Tabasco: Nacajuca, Centla, Centro, Macuspana) · Mexico (Oaxaca: Sierra and coast of the Tehuantepec region)
language family or group - Chuj
Guatemala (Huehuetenango: San Mateo Ixtatán, San Sebastián Coatán, Nentón) · Mexico (Chiapas)
- Náayeri
Mexico (Nayarit: Del Nayar, Sierra del Nayar; Durango)
- Dbaku
Mexico (Oaxaca: Cuicatlán district, including San Juan Tepeuxila and Santa María Pápalo)
- Enlhet
Paraguay (Presidente Hayes, Boquerón)
- Enxet
Paraguay (Presidente Hayes)
- Garifuna
Honduras (Caribbean coast) · Guatemala (Livingston, Puerto Barrios) · Belize (Stann Creek, Toledo)
- Tének
Mexico (San Luis Potosí; northern Veracruz)
- Wixárika
Mexico (Jalisco, Nayarit, Durango, Zacatecas)
- Itza'
Guatemala (Petén: San José, San Andrés)
- Ixil
Guatemala (Quiché: Nebaj, Chajul, Cotzal)
- Popti'
Guatemala (Huehuetenango: Jacaltenango, Concepción Huista, San Antonio Huista, Petatán and nearby) · Mexico (Chiapas)
- K'iche'
Guatemala (Quiché, Totonicapán, Quetzaltenango, Sololá, Suchitepéquez, Retalhuleu and other departments)
- Kaqchikel
Guatemala (Chimaltenango, Sacatepéquez, Sololá, Guatemala department, parts of Escuintla and Baja Verapaz)
- Maká
Paraguay (Central department near Asunción, Presidente Hayes)
- Qyol Mam
Guatemala (Huehuetenango, San Marcos, Quetzaltenango, Retalhuleu) · Mexico (Chiapas)
- Manjui
Paraguay (Boquerón, near the Pilcomayo River) · Argentina (Salta)
- Jñatrjo
Mexico (State of Mexico: San Felipe del Progreso, San José del Rincón, Ixtlahuaca, Atlacomulco; Michoacán) · Mexico City (migrant communities)
- Mazatec
Mexico (northern Oaxaca: Sierra Mazateca, Huautla de Jiménez; Puebla; Veracruz)
language family or group - Mbya ayvu
Paraguay (eastern departments including Caaguazú, Caazapá, Guairá, Itapúa, Alto Paraná) · Argentina (Misiones) · Brazil (southern and south-eastern states)
- Miskitu
Nicaragua (North and South Caribbean Coast Autonomous Regions: Bilwi/Puerto Cabezas, Waspam, Río Coco) · Honduras (Gracias a Dios, La Mosquitia)
- Ayuujk
Mexico (Oaxaca: Sierra Mixe, including Tlahuitoltepec, Totontepec, Ayutla, Zacatepec, Juquila Mixes)
language family or group - Tu'un Savi
Mexico (Oaxaca, Guerrero, Puebla; migrant communities in Baja California and Mexico City) · United States (California and other states)
language family or group - Mopan
Belize (Toledo, Stann Creek, Cayo) · Guatemala (Petén: San Luis, Poptún, Dolores)
- Nicaraguan Creole English
Nicaragua (Caribbean coast: Bluefields, Pearl Lagoon, Corn Islands, Bilwi/Puerto Cabezas)
- Nivaclé
Paraguay (Boquerón, Presidente Hayes) · Argentina (Salta)
- O'odham
United States (southern and central Arizona) · Mexico (northern Sonora)
- Hñähñu
Mexico (Hidalgo, Querétaro, State of Mexico, Veracruz, Puebla, Guanajuato, Michoacán, Mexico City)
language family or group - Pai Tavytera
Paraguay (Amambay, Concepción, San Pedro) · Brazil (Mato Grosso do Sul, as Kaiowá)
- Ngiwa
Mexico (southern Puebla: Tehuacán valley area, including San Marcos Tlacoyalco, Los Reyes Metzontla, San Felipe Otlaltepec, San Juan Atzingo)
language family or group - Popoluca
Mexico (southern Veracruz: Soteapan, Hueyapan de Ocampo, Sayula de Alemán, Oluta, Texistepec)
language family or group - Poqomam
Guatemala (Guatemala department: Mixco, Chinautla; Escuintla: Palín; Jalapa: San Luis Jilotepeque, San Pedro Pinula)
- Poqomchi'
Guatemala (Alta Verapaz: Tactic, Tamahú, Tucurú, San Cristóbal Verapaz, Santa Cruz Verapaz; Baja Verapaz: Purulhá)
- P'urhépecha
Mexico (Michoacán: Meseta Purépecha, Lake Pátzcuaro, Cañada de los Once Pueblos, Ciénega de Zacapu)
- Q'anjob'al
Guatemala (Huehuetenango: Santa Eulalia, San Juan Ixcoy, San Pedro Soloma, Santa Cruz Barillas) · Mexico (Chiapas, Campeche, Quintana Roo)
- Q'eqchi'
Guatemala (Alta Verapaz, Petén, Izabal, northern Quiché, Baja Verapaz) · Belize (Toledo) · Mexico (small communities)
- Sakapulteko
Guatemala (Quiché: Sacapulas)
- Sanapaná
Paraguay (Presidente Hayes, Alto Paraguay, Boquerón)
- Sipakapense
Guatemala (San Marcos: Sipacapa)
- Tektiteko
Guatemala (Huehuetenango: Tectitán, Cuilco) · Mexico (Chiapas: Mazapa de Madero, Amatenango de la Frontera)
- Me'phaa
Mexico (Guerrero: La Montaña and Costa Chica, including Malinaltepec, Tlacoapa, Acatepec, Zapotitlán Tablas, Azoyú)
language family or group - Tojol-ab'al
Mexico (Chiapas: Las Margaritas, Comitán, Altamirano, La Independencia, La Trinitaria)
- Tutunakú
Mexico (northern Veracruz: Papantla, Coyutla, Espinal; Sierra Norte de Puebla: Zapotitlán de Méndez, Huehuetla, Zihuateutla)
language family or group - Triqui
Mexico (western Oaxaca: San Juan Copala, San Andrés Chicahuaxtla, San Martín Itunyoso; migrant communities in Baja California and Mexico City) · United States (California and other states)
language family or group - Tz'utujil
Guatemala (Sololá: Santiago Atitlán, San Pedro La Laguna, San Juan La Laguna, San Pablo La Laguna; Suchitepéquez: Chicacao)
- Bats'il k'op
Mexico (Chiapas: Ocosingo, Chilón, Oxchuc, Tenejapa, Yajalón, Altamirano and other municipalities)
- Bats'i k'op
Mexico (Chiapas highlands: San Juan Chamula, Zinacantán, San Andrés Larráinzar, Chenalhó, Huixtán, San Cristóbal de las Casas and other municipalities)
- Uspanteko
Guatemala (Quiché: San Miguel Uspantán, Chicamán)
- Maaya t'aan
Mexico (Yucatán, Campeche, Quintana Roo) · Belize (north)
- Diidxazá
Mexico (Oaxaca: Valles Centrales, Sierra Norte, Sierra Sur, Isthmus of Tehuantepec; Veracruz; migrant communities in Mexico City) · United States (California and other states)
language family or group - Zoque
Mexico (north-west Chiapas: Copainalá, Tecpatán, Francisco León, Ocotepec, Chapultenango; Oaxaca: Chimalapas; Tabasco)
language family or group
